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side effect of justicia carnea

Plantcaretoday.com is a participant in the Amazon Services LLC Associates Program, an affiliate advertising program designed to provide a means for sites to earn advertising fees by advertising and linking to amazon.com, how to get rid of leaf eating caterpillar. The antidiabetic effect of justicia is through the inhibition of-amylase and -glucosidase, the carbohydrate metabolizing enzymes, and also through its hypolipidemic potential. Different drugs are used but many depend mainly on plants and herbal products for its treatment. It results from one or more of the following events: loss of red blood cells (RBCs), reduction in the production of RBCs, increased destruction of RBCs, and shorter life span of RBCs (McEvoy, 2013). We'll respect your privacy and unsubscribe at any time. The liver and kidney of rats administered with 500mg/kg JCEE and above demonstrated slight increase in MDA level with significant (P<0.05) increase only observed in the liver of rats that received 1200mg/kg of extract. View abstract. Inter J Biochem Cell Bio. Mean corpuscular hemoglobin (MCH) and mean corpuscular hemoglobin concentration (MCHC) showed significant (p<0.05) increased at 50mg/kg while doses greater than 100mg/kg showed no significant difference compared to the control. In traditional medicine, justicia carnea is used in treating hepatitis. Paradoxically, oxidation of GSH has been reported to occur when GSH interact with metal ions thereby generating superoxide anions from the transfer of electrons from the metal ions to molecular oxygen [32]. Absorbance reading was taken at 620nm regularly at an interval of 1min against reagent blank. J Ethnopharmacol 1984;12(1):93-111. 16. CAS Article The appropriate dose of Justicia pectoralis depends on several factors such as the user's age, health, and several other conditions. The liver and kidneys excised from all the experimental rats were fixed in a labeled sample bottles containing 10% formalin and processed for histological examination. List of various diseases cured by Justicia Betonica. Valko M, Leibfritz D, Moncol J, Cronin MTD, Mazur M, Telser J. 2015;6(7):265270. 2010;4(8):6804 https://doi.org/10.5897/JMPR09.487. Badami S, Aneesh R, Sankar S, Sathishkumar MN, Suresh B, Rajan S. Antifertility activity of Derris brevipes variety coriacea. Arch Toxicol. Research reports it isnt capable of causing kidney and liver damage either but dont eat it raw. Consumption of medicinal plants has diverse therapeutic benefits and could also have toxic effect. This research focused on the safety and in vivo antioxidant status of healthy albino rats exposed to J. carnea leaf ethanol extract. Tags: benefits of justicia carnea, health benefit of justicia carnea, justicia carnea . Oso BJ, Oyewo EB and Oladiji AT. However, lowest (50mg/kg) dose of extract significantly elevated MCH and MCHC. Venancio, E. T., Rocha, N. F., Rios, E. R., Feitosa, M. L., Linhares, M. I., Melo, F. H., Matias, M. S., Fonseca, F. N., Sousa, F. C., Leal, L. K., and Fonteles, M. M. Anxiolytic-like effects of standardized extract of Justicia pectoralis (SEJP) in mice: Involvement of GABA/benzodiazepine in receptor. For professional medical information on natural medicines, see Natural Medicines Comprehensive Database Professional Version. In this study, the aqueous leaf extract of Justicia carnea was used. Chariandy, C. M., Seaforth, C. E., Phelps, R. H., Pollard, G. V., and Khambay, B. P. Screening of medicinal plants from Trinidad and Tobago for antimicrobial and insecticidal properties. The hematopoietic systems represent a sensitive target of toxic compounds and an essential index of physiological and pathological status in experimental animals [24]. Joseph, H., Gleye, J., Moulis, C., Fouraste, I., and Stanislas, E. O-Methoxylated C-glycosylflavones from Justicia pectoralis. Further study assessing the kidney indices (urea, creatinine and electrolytes) is however encouraged to ascertain the safety of the plant extract on renal function. The resultant liquid would turn crimson red. 1978;90:819. It is not. The mixture was allowed to cool and centrifuged at 650g for 10min to obtain the supernatant. Justicia pectoralis seems to have antibacterial and anti-inflammatory effects. The Pros and Cons of Creatine You Should Know. Buege JA, Aust SD. The compound responsible for this activity is lignan. The protein content may help in cellular functions and are building blocks for structural and functional biomolecules. long (20 cm), densely packed with pink to crimson tubular flowers. It is believed by local consumers in Ghana to possess anti-anaemic effects that boost blood levels in pregnant women, anaemic patients and also . Decreased white blood cell count was obtained in this report, the level of lymphocyte and granulocyte was not altered by the extract while MID sized cell was significantly elevated at 500 and 800mg/kg dose. Extinction coefficient () of MDA TBA complex=1.56105M1cm1. 8-10 Justicia carnea leaves. Rats in the 3 different groups received 10, 100 and 1000mg/kg body weight of JCEE orally using oral gavage. Justicia pectoralis is a flowering herb that grows in tropical areas of the Americas, including South and Central America. OTHER NAME(S): Achille Millefeuille, Achille Mille-Feuille, Ana. Each rat was dissected and blood samples were collected by cardiac puncture using 5mL into tubes containing ethylenediaminetetraacetic acid (EDTA) for hematological analysis. Acta Scientiarum Polonorum, Technologia Alimentaria. Tietz NW. The Justicia carnea leaves are rich in B-vitamins. When you boil the plant, it turns the water red. Anyone you share the following link with will be able to read this content: Sorry, a shareable link is not currently available for this article. if you add justicia carnea leaves in avocado seed tea, you may just get yourself the best remedy for cardiovascular diseases. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. The plant is transplanted in the spring. Whether added to garden beds or pots, the justicia (plant) adds a colorful tropical touch and are easy to grow. The plant has various other common names including: Back in the day, the Justicia flower was boiled and used to solve anemia problems. Briefly, 1.0ml of the sample was mixed with 2ml of TCA-TBA-HCl reagent (0.37% thiobarbituric acid, 15% trichloroacetic acid and 0.24N HCl in 1:1:1) and boiled at 100C in a water bath for 15min. [1] The perennial plant is native to the Atlantic Forest ecoregions of eastern Brazil . Another strong benefits of justicia carnea leaves is in lipid profile. Treatments of all experimental animals were performed following Principle of Laboratory Animal Care manual guidebook of National Institute of Health as approved by the Research Ethics Committee of Olusegun Agagu University of Science and Technology, Okitipupa, Ondo State. The liver and kidneys were excised and rinsed immediately in a normal saline (0.9% Nacl) to remove blood stain, dried between layers of Whatman filter paper, weighed and homogenized to obtain the supernatant for biochemical analysis. Leal, L. K., Ferreira, A. The effect of the ethanol extract of Justicea. Ewe eje is safe and healthy for consumption. The Health benefit of Ewe eje (Justicia carnea leaf) are highlighted in this article. The shrubby habit of the plant is well-suited for both containers and outside planting. 15 Amazing benefits of brocoli juice and side effects. Details on Purple Shield plant care. Cassani, J., Dorantes-Barrn, A. M., Novales, L. M., Real, G. A., & Estrada-Reyes, R. (2014). The lush foliage and distinctive flowers make Brazilian Plume a natural for a tropical garden. Methods. In a reaction mixture containing 0.01M phosphate buffer (pH7.0), 0.5ml of 0.2M H2O2 and 0.4ml distilled water, 0.5ml of sample was added. Data were analyzed using one-way analysis of variance (ANOVA) using Statistical Product and Service Solutions (SPSS) version 17.0 and results were expressed as meanSEM. Privacy This leaf replenishes your blood supply immediately. Too much sun can scorch the leaves, and too little will result in fewer flowers. This plant is somewhat drought-tolerant once established but looks best with regular watering during periods of extended dry weather. Summer temperatures above 77 degrees Fahrenheit (25 C) are perfect. 2005 - 2023 WebMD LLC, an Internet Brands company. Ethanol extract of J. carnea leaf elevated red blood cell, hemoglobin, packed cell volume and platelet count with significant increase at higher doses of extracts compared to the control. The weight of organs (liver and kidney) reduced steadily in a concentration dependent manner. Antianaemic potentials of some plant extracts on phenyl hydrazineinduced anemia in rabbits. View abstract. He has B.Sc.,and M.Sc. This is why you should avoid potting them if you live in colder areas. Grows up to 4-6 ft. tall (120-180 cm) and 2-3 ft. wide (60-90 cm). It is also known as Jacobinia carnea, and is a part of the Acanthaceae family along with the Aphelandra squarrosa (Zebra plant) and Crossandra. 2011;5(9):48992 https://academicjournals.org/journal/AJPS/article-full-text-pdf/6AA410310867. [4].Inflammationinjuries, in an attempt to heal is presented by five cardinal signs of heat (calor), redness (rubor), swelling (tumor), pain (dolor) and loss of function5.Studieshave demonstrated inflammation as being caused by Part of Due to the local availability, easy access and relatively low cost, medicinal plants are gaining attentions in health care programmes. According to acute toxicity grading standards, LD50 of substances greater than 5000mg/kg is practically considered non-toxic [22, 23]. When it comes to blood boosting and treatment of anemia, justicia carnea has proven beyond doubt to be an effective remedy. Article ID 687197, 2013; p. 13. https://doi.org/10.1155/2013/687197. Corra, GM., de C. Alcntara, AF. While histology of organs showed no adverse pathological lesions in the internal organs of rats, higher dose (1200mg/kg) over a period of time could cause noticeable liver and kidney injury. Oral acute toxicity study on J. carnea ethanol extract (JCEE) was carried out according to Lorke [15] method using the total of twelve (12) albino rats in two phases. The findings show that ethanol extracts of Costus afer and Justicia carnea could operate as main antioxidants and free radical scavengers. Studies have shown that ewe eje contains antioxidant and cardio-protective properties. Safety assessment of Uvaria chamae root extract: acute and subchronic toxicity studies. Different researches performed on wistar rats has proven the non toxicity of justicia carnea. Anaemia is a common blood disorder that affects people of all ages, though people at greater risk are the elderly, young women and infants. One of the oldest known plant is the fig tree. In these groups, from mild to severe order; shows observable congested portal vein, the liver parenchyma showed area of harmorrhage, the morphology of the hepatocytes appear pyknotic, some show mild fat infiltration (red arrow) the sinusoids appear fibrotic with infiltration of inflammatory red cells (red arrow). Only plants will be removed from the collection. 2008;108(9):14807. It is an awesome plant and worth your time and attention. Not sure which Justicia to pick?Compare All Justicia. Ethanol extracts of J. carnea leaf increased RBC, hemoglobin and platelet with significant increase (p<0.05) in groups that received higher dose (>500mg/kg b.w) of extract compared to the control. The weight of liver and kidney of rats were measured immediately after excising the organs and is presented in Table2. How often should it be watered? The absorbance was taken at interval of 1min for 3min at 480nm. Over time, they cause atherosclerosis and myocardia infarction. Biochem Pharmacol. Lipid peroxidation was determined by measuring the formation of thiobarbituric acid reactive substances (TBARS) according to the method described by Buege and Aust [20]. The non significant decrease observed in this study is in consonance with the work of Onyeabo et al., [9] who also reported no significant difference in the relative weights of liver and kidney. The haematological indices of the blood samples were determined using an automated URIT 2900 Plus 3 Differential Haematological Analyzer. When the Jacobinians are newly planted, water them daily for a few weeks. These animals were obtained from the animal house of the Department of Chemical Sciences, Ladoke Akintola University of Technology Ogbomoso Oyo State, Nigeria. 50mg/kg-1200mg/kg treatment relative to control treatment showed varied degree of renal injury that is dose dependent. 2008;79:3326 https://doi.org/10.1016/j.fitote.2008.02.005. The leaves are rich in carbohydrates and proteins, which are for energy production and maintenance of cellular activities. Ewe eje or Ewe ajeri is known by the Igbo tribe as Ogwu obara. Feed the soil when the cutting is new to encourage better growth. Justicia carnea is a popular ornamental plant, which possesses powerful medicinal values. leaf inhibits interferon-γ secretion and has bacteriostatic activity against Acinetobacter baumannii and Klebsiella pneumoniae. Keep the soil moist, but not waterlogged. 5. 2007;112(1):13844. From this study, the significant increase in platelet counts suggested that the extract could be useful in preventing excessive blood loss (through blood clotting) and resistance of capillary membranes to leakage of red cells when blood vessels are damaged. However, serious caution of the dose should be taken into consideration when extrapolating this result for human consumption. A cup of ewe eje extract in the morning will provide you with energy needed to pull through the days activities. 1983;53:27589. In its native habitat, the Justicia carnea plant grows upright and may reach 3 5 feet tall. I am a practicing medical doctor, a philosopher, critical thinker, a globalist, a patriot, SEO expert and a patient blogger. The leaves of Justicia carnea contains powerful antioxidant activities and phytochemical components that help reduce oxidative stress, and reduce the risk of development of cancer. It may be, judging from the antidepressant activity of other plant of justicia species whose activity have been studied, proper to state that justicia carnea may possess antidepressant properties. J Ethnopharmacol 1985;13(1):3-49. Justicia carnea (Brazilian Plume) is an upright, evergreen shrub with large, dark green leaves, 10 in. Effect of methanol leaf extract of Justicia carnea on serum albumin (ALB) and total protein (TP) concentration CCl 4 intoxicated rats. Turn off the heat and then soak the leaves into the pot. Manage cookies/Do not sell my data we use in the preference centre. Never delay or disregard seeking professional medical advice from your doctor or other qualified health care provider because of something you have read on WebMD. In a study conducted by Onyeabor and colleagues, the leaf extract of jusiticia carnea reverses the anemic effect of phenylhydrazine on the pack cell volume, red blood cell, and hemoglobin concentrations. A., Bezerra, G. A., Matos, F. J., and Viana, G. S. Antinociceptive, anti-inflammatory and bronchodilator activities of Brazilian medicinal plants containing coumarin: a comparative study. Justicia pectoralis is a flowering herb that grows in tropical areas of the Americas, including South and Central America. Justicia carnea, the Brazilian plume flower, Brazilian-plume, flamingo flower, or jacobinia, is a flowering plant in the family Acanthaceae. The antioxidants in Justicia carnea helps protect the liver and the heart from toxic agents and free radicals. Sun M, Zigma S. An improved spectrophotometer assay of superoxide dismutase based on epinephrine autoxidation. Excitedly, scientific studies have supported the traditional claims. The results of this study suggests that ethanol extract of J. carnea leaf is relatively safe, could be beneficial in alleviating hematology related abnormalities without causing adverse effects on endogenous antioxidant system. What this means is that aside fighting anemia, justicia carnea leaves also improves your cardiovascular health by suppressing the tendency for dyslipidemia. Terms and Conditions, Chemical constituents and biological activities of species of Justicia a review. Prevent this by spraying the leaves with water. The reaction is terminated by the addition of 2ml of dichromoacetic acid mixture (potassium dichromate (5%) and glacial acetic acid; 1:3v/v) and heated at 60C for 10min. Side Effects, Uses and Health benefits of Ewe eje (Justicia carnea leaf), The exact topic of this article first appeared on www.nimedhealth.com.ng. Maturitas 2010;66(3):315-322. The leaves of justicia carnea possess high content of iron and vitamin C. This compounds may be responsible for the blood boosting property of ewe eje leaves. J Ethnopharmacol. Acute and sub-acute toxicity studies of aqueous and methanol extracts of Nelsonia campestris in rats. Chidubem Olovo is a biochemist and a researcher whose interest is centered on the chemistry of natural products, their pharmacological properties and how using the plant sources can improve human healthy living. Prepare the existing soil by breaking it up with a spade or hoe. As for light exposure, keep the plant away from the full sun. Microsomal lipid peroxidation. Results obtained from the acute oral toxicity study revealed tolerance of experimental rat to acute administration of J. carnea ethanol extracts since no mortality and signs of toxicity were observed after 24h (Table1). Safety assessment of oral administration of ethanol extract of, $$ \mathrm{Total}\ \mathrm{protein}\kern0.5em =\kern0.5em \frac{\mathrm{Absorbance}\ \mathrm{of}\ \mathrm{sample}}{\mathrm{Absorbance}\ \mathrm{of}\ \mathrm{standard}}\kern0.5em \times \kern0.5em \mathrm{Concentration}\ \mathrm{of}\ \mathrm{standard} $$, $$ \mathrm{Catalase}\ \mathrm{activity}\ \left(\mathrm{U}/\mathrm{ml}\right)=\kern0.5em \frac{\Delta \mathrm{A}/\min \kern0.5em \times \kern0.5em \mathrm{TV}}{\upvarepsilon \kern0.5em \times \kern0.5em \mathrm{SV}\kern0.5em \times \kern0.5em \mathrm{TP}} $$, $$ \mathrm{SOD}\ \mathrm{activity}\ \left(\mathrm{U}/\mathrm{ml}/\mathrm{mg}\ \mathrm{protein}\right)\kern0.5em =\kern0.5em \frac{\Delta \mathrm{A}/\min \kern0.5em \times \kern0.5em \mathrm{TV}}{\upvarepsilon \kern0.5em \times \kern0.5em \mathrm{SV}\kern0.5em \times \kern0.5em \mathrm{TP}} $$, $$ \mathrm{Concentration}\kern0.5em \mathrm{of}\kern0.5em \mathrm{reduced}\kern0.5em \mathrm{GSH}\kern0.5em =\kern0.5em \frac{\left(\Delta \mathrm{A}\kern0.5em \times \kern0.5em \mathrm{TV}\right)}{\left(\upvarepsilon \kern0.5em \times \kern0.5em \mathrm{SV}\kern0.5em \times \kern0.5em \mathrm{TP}\right)} $$, $$ \mathrm{Malondialdehyde}\kern0.5em =\kern0.5em \frac{\left(\mathrm{A}\kern0.5em \times \kern0.5em \mathrm{TV}\right)}{\Big(\upvarepsilon \kern0.5em \times \kern0.5em \mathrm{SV}\kern0.5em \times \kern0.5em \mathrm{TP}} $$, https://doi.org/10.1186/s40816-020-00234-4, https://doi.org/10.1016/j.jep.2015.06.005, https://doi.org/10.1016/j.joad.2015.08.006, https://doi.org/10.1016/j.jep.2005.06.013, https://doi.org/10.3109/08860220903367585, https://doi.org/10.1590/S0102-695X2011005000196, https://academicjournals.org/journal/AJPS/article-full-text-pdf/6AA410310867, https://doi.org/10.35841/biomedicalresearch.30-18-666, https://doi.org/10.1016/j.jep.2007.02.011, https://doi.org/10.1186/s40816-019-0104-4, https://doi.org/10.1016/j.fitote.2008.02.005, https://doi.org/10.1016/j.jada.2008.06.430, https://doi.org/10.1016/j.biocel.2006.07.001, https://doi.org/10.1186/s12906-015-0760-y, http://creativecommons.org/licenses/by/4.0/. Chanda S, Parekh J, Vaghasiya Y, Dave R, Baravalia Y, Nair R. Medicinal plants - from traditional use to toxicity assessment: a review. Rather it can assist with improveing liver function such as detoxification. In conclusion, oral acute administration of J. carnea ethanol extract is safe because neither mortality nor any signs of toxicity were observed in experimental rats. The plant possess several bioactive compounds like polyphenols, which act as antioxidants or anti-inflammatory compounds. Justicia carnea needs bright, indirect light to thrive. This requires more attention to properly document the various health benefits of justicia carnea. Corroborating with the results of the antioxidant system and weight of the liver, continuous exposure to higher dose (1200mg/kg) of JCEE could result in hepatic damage. Keep in mind that natural products are not always necessarily safe and dosages can be important. The result of hematology indices is presented in Table3. It has been reported previously that under certain conditions, dietary antioxidants such as ascorbic acid, tocopherol and carotenoids could act, occasionally, as pro-oxidants to initiate slight degree of oxidative stress microenvironment. J Nat Prod 1988;51(4):804-805. The higher LD50 (>5000mg/kg body weight) of J. carnea leaf ethanol extract suggested that the ethanol extract is experimentally safe and not toxic. Assessment of Aloe vera (L) genotoxic potential on Escherichia coli and plasmid DNA. In the kidney, SOD and MDA level were indistinguishable compared to the control except SOD level in rats that received 800mg/kg JCEE that reduced significantly (p<0.05). California Privacy Statement, 2015;174:61827 https://doi.org/10.1016/j.jep.2015.06.005. Photomicrograph of a liver sections stained with Haematoxylin and Eosin (Mag. Also, remove old flowers to keep the plant healthy. Mukinda JT, Syce JA. Summarily, experimental group shows some degenerative changes that can be termed as necrosis, some mild fibrosis and hemorrhage characterized by the presences of infiltrated red hemorrhagic and inflammatory cells. 2013;1:38898. This is in agreement with study of Anthonia et al., [21] who obtained LD50 above 5000mg/kg for aqueous extracts of J. carnea leaf. Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. Radhika J, Sathya S, Jothi G, Japasheba JL. Organic extract of Justicia pectoralis Jacq. Also present in the leaf extract are minerals (such as magnesium, copper, iron, zinc, calcium); and vitamins (such as vitamins A, C, E and B-vitamins). Another plant with this benefit is fertility tree. The Brazilian Plume is native to mainly tropical areas in South America, meaning it thrives in warm and slightly humid climates. CONDITIONS OF USE AND IMPORTANT INFORMATION: This information is meant to supplement, not replace advice from your doctor or healthcare provider and is not meant to cover all possible uses, precautions, interactions or adverse effects. Infertility after therapy, in particular, imposes a significant mental strain on young patients. White blood cell counts usually increases following foreign invaders (pathogens) resulting in normal body physiological response which boost the bodys defense mechanisms [28, 29]. You should always speak with your doctor or health care professional before you start, stop, or change any prescribed part of your health care plan or treatment and to determine what course of therapy is right for you. Generally disease free. J Afr Ass Physiol Sci. van Andel T., Carvalheiro LG. Prof. F.O. Regular intake can reduce your risk of liver diseases like liver cirrhosis, hepatitis and liver inflammation. Some people would rather chew the leaves, while others add to meals or brew into a tea (in combination with other plants). 3. All rights reserved. de Vries, J. X., Tauscher, B., and Wurzel, G. Constituents of Justicia pectoralis Jacq. Mr. K.O. hindawi publishing corporation evidence-based complementary and alternative medicine. The plant looks great along garden borders and near building foundations. In which ever condition, the blood glucose level increases abnormally. The ability of glutathione to regenerate these dietary antioxidants has been linked to the redox state of glutathione disulphide-glutathione couple (GSSG/GSH) ratio [31]. Liver and kidney are the main targets of toxicants because they are respectively involved in biotransformation and excretion of xenobiotics. Fitoterapia. The resultant liquid after boiling is usually crimson red. 2004;19(12):16. 200, 500 and 1000 mg/kg bw of Justicia carnea showed a significant (p<0.05) decrease in the activities of ALT, AST and ALP, and bilirubin level while total protein and albumin levels increased significantly (p<0.05) when compared with the rats treated with CCl alone. View abstract. Google Scholar. Springer Nature. Akintimehin is a lecturer in the Biochemistry unit of Chemical Sciences Department, Olusegun Agagu University of Science and Technology, Okitipupa, Ondo State, Nigeria. Rats were routinely observed for signs of toxicity. 2005;102(2):197201. It is also composed of vitamins and minerals good for heart health. Relative to control, lymphocyte and granulocyte exhibited no significant difference in all doses while MID was elevated in treated groups with significant increase in rats administered with 500 and 800mg/kg body weight. READ ALSO: How long does it take for Aju mbaise to work. The changing faces of glutathione, a cellular protagonist. Google Scholar. Olumese FE, Onoagbe IO, Eze GI, Omoruyi FO. Braz. -Amylase binding-interaction with JCAE was also investigated using fluorescence spectroscopy and molecular docking. However, there have not been scientific backing on this claim, yet, from the antiviral properties of other species of justicia, it could be that this plant possess antiviral properties which is utilized in the treatment of hepatitis infection. Local consumers of the leaves are mostly . In the study conducted by Onyeabor and his colleagues, it was shown that the leaf extract not only reverses anemic condition, but also lowered the lipid profile of the experimental rats. The unique and beautiful tubular flowers of Justicia carnea highlight the plant. The cuttings are taken from the parent plant in the spring after the plant has bloomed. It is very rich in iron, a major component is RBC hemoglobin. When there is high cholesterol level in your blood, LDL- and VLDL- cholesterols are being deposited on the arterial wall of blood vessels, thereby blocking free flow of blood and increasing blood pressure. Ewe eje is good for the liver. Despite the avalanche use of medicinal plant, preliminary toxicity studies remain essential tools to ensure safe consumption and prevent unexpected toxicity that could arise from long term exposure. https://doi.org/10.1016/j.jep.2007.02.011. 10.9734/ijbcrr/2020/v29i630194. The spread is equally glorious and can take up 12 15 inches of space. But like in the case of depression and hepatitis, other species of justicia have been studied and proven to be antiepileptic. Several medicinal plants such as Xylopia aethiopica [25], Tectona grandis [26] and extracts of M. indica, A. hybridus and T. occidentalis [27] have also been reported to elevate RBC, hemoglobin and packed cell volume. The plants cannot be propagated with seeds. https://doi.org/10.13040/IJPSR.0975-8232. This is attributed to the anti-hyperlipidaemic properties of the plant. Side effects of Ewe eje (Justicia carnea leaf Side Effects) Ewe eje is safe and healthy for consumption. 2015;15:236. https://doi.org/10.1186/s12906-015-0760-y. It also can be used in combination with other vegetables such as the Efinrin (scent leaves), ugwu etc. aqueous extract J. carnea leaves and its effects on haematological and some biochemical indices of anaemia induced male Wistar albino rats. Justicia carnea (ewe eje) is used by pregnant women to boost the production of red blood cells and cure anemia in pregnancy. Despite the therapeutic importance of medicinal plants, toxic substances have been shown to be present in large numbers of plants investigated [3]. Research reports it isn't capable of . Haematological and biochemical studies on Justicia carnea leaves extract in phenylhydrazine induced-anemia in albino rats. In phase two, three rats were separated into 3 groups of one rat per group. Estimation of total, protein-bound, and non-protein sulfhydryl groups in tissues with Ellmans reagent. Inflammation is a complex biological response of body's tissue to harmful stimuli like infections, toxins and itself. SOD is involved in the dismutation of the highly reactive superoxide anion to molecular oxygen (O2) and to less reactive hydrogen peroxides (H2O2) species, whereas CAT removes hydrogen peroxide (H2O2) and toxic hydroxyl radical into water molecule [35]. 3rd ed. Akintimehin, E.S., Karigidi, K.O., Omogunwa, T.S. In the winter, temperatures between 60 64 degrees Fahrenheit (15 18 C) are ideal. Ewe eje improves the production of white blood cells and other antibodies, all which are essential for strengthening immunity. This suggested that the extract did not alter tissue function in converting harmful hydrogen peroxide to water and oxygen. The aqueous leaf extract of ewe eje has demonstrated hypoglycaemic and antidiabetic properties; and thus, can be said to assist with blood sugar levels reduction. By using this website, you agree to our In some areas, the plant may tolerate temperatures as low as 50 degrees Fahrenheit (10 C). Authors KOK and ESA performed the statistical analysis and managed the analyses of study. J Ethnopharmacol 2000;70(2):151-159. The presence of blood boosting nutrients such as iron, copper, zinc and vitamin C can help prevent iron-deficiency anaemia and other anemic conditions. Ewe eje or ewe ajeri is prepared differently by different folks. Adetuyi is a Professor of Biochemistry in the Department of Chemical Sciences, Faculty of Sciences, Olusegun Agagu University of Science and Technology, Okitipupa, Ondo State, Nigeria.

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side effect of justicia carnea